TA25-Image Guided Stereotactic radiosurgery

From Linac based to Gamma Knife to CyberKnife

Cheng Yu, Ph.D.

Professor and Director of Physics

Department of Radiation Oncology

Keck School of Medicine

University of Southern California

Los Angeles, California

Stereotactic radiosurgery was first introduced in 1951 by Lars Leksell, who developed Gamma Knife in the late 1960’s. In the early days of stereotactic radiosurgery, a single fraction of high radiation dose was delivered to a well-defined small intracranial target, which was immobilized by using a headframe. In 1988, the concept of image-guided frameless SRS was proposed by John Adler, who subsequently designed and developed the CyberKnife system. In this presentation, the history of the development of stereotactic radiosurgery will be briefly reviewed, followed by our experience with stereotactic radiosurgery using the linac based, Leksell Gamma Knife systems. Finally, our experience with stereotactic radiosurgery for both intracranial and extracranial lesions using the image guided CyberKnife system will be presented.

TA25－图像引导的立体定向放射外科

从基于加速器的系统到伽玛刀到赛博刀

Cheng Yu, Ph.D

Professor and Director of Physics

Department of Radiation Oncology

Keck School of Medicine

University of Southern California

Los Angeles, California

Lars Leksell于1951年首先提出了立体定向放射外科的概念，他在二十世纪六十年代后期开发了伽玛刀。在实施立体定向放射外科的早期，通常通过头架固定对精确定义的小的颅内靶区实施单分次、高剂量照射。在1988年，John Adler提出了图像引导、无框架立体定向放射外科的概念, 随后他设计并开发了赛博刀系统。本报告将简单回顾一下立体定向放射外科的发展历史，随后介绍我们使用基于加速器的的系统和Leksell伽玛刀系统进行立体定向放射外科的经验。最后将介绍我们使用图像引导的赛博刀系统进行颅内和颅外病变立体定向放射外科的经验。